Liraglutide

[CAS KORE. ] 204656-20-2
[Tātai Molecular] C172H265N43O51
[Taumaha Molecular] 3751.262
[Ahua] Paura Ma
[Pure] 99%

[Mahi]
1. Whakanuia te whakapaunga kaha, whakaitihia te taumaha;
2. Whakaitihia te hiahia, te whakanui i te makona, na reira ka whakaiti i te horomanga o te calorie, te whakaroa i te noho puhanga o te kopu me te motireti gastrointestinal;
3. Te whakatairanga i te whakahiato me te hunanga o te insulin;
4. Te aukati i te hunanga o te glucagon;
5. Tiakina nga pūtau β me te whakanui ake i te maha o nga pūtau β;
6. he painga o te whakaheke toto;
7. Ka tino whakahekehia te katoa o te cholesterol, triglycerides, me nga taumata LDL
8. Te tiaki ngakau;

Mo Liraglutide
Ko te Liraglutide he rite ki te glucagon-like peptide-1 (GLP-1) o te tangata e whakamahia ana mo te maimoatanga o te mate huka. Ko te Liraglutide he tairitenga GLP-1 me te 97% te raupapa homology ki te GLP-1 tangata, ka taea te here me te whakahohe i nga kaiwhakawhiwhi GLP-1. Ko te kaiwhakawhiwhi GLP-1 te whaainga o te GLP-1 maori, he homoni incretin endogenous e whakatairanga ana i te hunanga o te insulin e whakawhirinaki ana ki te huka mai i nga pūtau β pancreatic. Kaore i rite ki te GLP-1 taiao, ko nga rongoako me te rongoa rongoa o te liraglutide i roto i te tangata e pai ana mo te tikanga whakangao mo ia ra.
Ko te mahi o te liraglutide ka takawaenga e tana taunekeneke motuhake me te kaiawhina GLP-1, na te pikinga o te cyclic adenosine monophosphate (cAMP). Ka taea e te Liraglutide te whakaihiihi i te hunanga o te insulin i runga i te tikanga e whakawhirinaki ana ki te kukū o te huka, me te whakaheke i te nui o te glucagon i runga i te tikanga e whakawhirinaki ana ki te hukahuka. No reira, ka piki te huka toto, ka whakaihiihihia te hunanga o te insulin i te wa e peehia ana te hunanga o te glucagon. Engari, ka taea e te liraglutide te whakaheke i te hunanga o te insulin i te wa o te hypoglycemia me te kore e pa ki te hunanga o te glucagon. Ko te tikanga hypoglycemic o te liraglutide kei roto ano hoki te roanga o te wa putunga o te kopu. Ka whakahekehia e te Liraglutide te taumaha tinana me te papatipu ngako tinana ma te whakaiti i te hiakai me te kaha o te kai. Ka taea e Liraglutide te whakaheke i te huka toto, te whakahaere i te kai me te whakaroa i te putunga puku. Ka taea e ia te whai waahi awhina ki te whakaheke taumaha me te whakaora i nga tohu o te momona.
Ka taea hoki e te Liraglutide te pehi i te hiahia, te whakaroa i te putunga o te kopu, te whakaheke i te kai calorie, me te awhina ki te whakahaere i te taumaha. Kaore e taea e Liraglutide te whakaheke i te huka toto me te whakahaere i te taumaha o te tinana, engari ka whakapai ake i te pehanga toto, te toto toto me etahi atu mea morearea mo te mate ngakau coronary. Ka taea hoki te whakaiti i te taumaha o te tinana me te whai hua tiaki ki te mate ngakau. Ka whakamahia te Liraglutide ki te rongoa i te mate huka momo 2, ina koa nga turoro momo me te nui o te aukati insulin, he mea whai hua ki te whakaheke i te parenga o te insulin me te whakapai ake i te maarama o te insulin.