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[ Raupapa ] Sar-Arg-Val-Tyr-Val-His-Pro-Ala
[CAS KORE. ] 34273-10-4
[Tātai Molecular] C42H65N13O10
[Taumaha Molecular] 912.05
[Ahua] Paura Ma
[Pure] 98%

[Mahi]
He aukati whakataetae tino motuhake o te angiotensin II ka whakamahia ki te taatai ​​​​o te whakaheke toto.

Mo Saralain
Ko te Saralasin, e mohiotia ana ko te saralasin tetratricopeptide repeat domain peptide (TPR), he peptide waihanga i hangaia i te tuatahi hei kaihoko antihypertensive. I ahu mai i te angiotensin II, he taiaki e whai waahi ana ki te whakahaere i te pehanga toto.
Ka mahi a Saralasin hei kaiwhakataetae whakataetae mo nga kaiwhakawhiwhi angiotensin II, ina koa ko te momo angiotensin momo 1 (kaiwhakawhiwhi AT1). Na roto i te here me te aukati i te kaiwhakawhiwhi AT1, ka aukati te saralasin i te herenga o te angiotensin II me te aukati i ona paanga whaiaroaro.
Ko te whakamahinga matua o te saralasin kei roto i nga rangahau me nga waahi whakamatautau ki te ako i te punaha renin-angiotensin-aldosterone (RAAS) me tana mahi i roto i te ture whakaheke toto. Kua whakamahia ki te tirotiro i nga paanga o te aukati i nga kaiwhakawhiwhi angiotensin me te tirotiro i nga tikanga o te whakaheke toto.