Tertomotide

Hokona te peptide Tertomotide Ipurangi i te utu hokohoko. Tukunga wheketere. Tikina te utu hou. Uiui Inaianei!
Hokona te Tertomotide mai i te Kaihanga/Kaituku, Hei Hoko, Utu, Tuku - Bolise.

[ Ingoa Kē ] GV1001
[CAS KORE. ] 915019-08-8
[Tātai Molecular] C85H146N26O21
[Taumaha Molecular] 1868.26
[Ahua] Paura Ma
[Pure] ≥98%

[Mahi]
1. Anti-mumura;
2. Huaora;
3. Ngā mahi ārai-mate pūkahukahu me te tautoko-ora;
4. Te whakapai ake i te mahi hinengaro;

Mō Tertomotide
Ko te Tertomotide (CAS: 922174-60-5), e mōhiotia ana ko GV1001, he peptide waikawa amino 16-hangai i ahu mai i te pae whakaterenga (ngā toenga 611–626) o te telomerase reverse transcriptase tangata (hTERT). He tino wairewa ki te wai, he pumau mō te rokiroki roa i te -20°C i roto i ngā āhuatanga hiri, ā, e whakamahia ana i roto i ngā rangahau pūtaiao. I whakawhanakehia tuatahitia hei kano ārai mate pukupuku rongoā, ko tōna maha o ngā mahi ahurei kua arahina ki tana tono i roto i ngā mara kanorau - pēnei i te rangahau mate neurodegenerative me te whakahaere koroheketanga - ka waiho hei pokapū o te rangahau pūtaiao maha-mātauranga.
Ko tētahi āhuatanga matua o Tertomotide ko tōna kaha ki te here ki ngā ngota MHC-I me MHC-II, ka whakahohe i ngā pūtau T āwhina CD4⁺ me ngā pūtau T paitini CD8⁺ hei whakaoho i tētahi urupare ārai mate motuhake ki ngā pūtau pukupuku telomerase-pai. Ahakoa kua whakaranua ngā hua o te whakamātautau haumanu e pā ana ki tōna whakamahinga me te chemotherapy mō ngā momo mate pukupuku, kua whakaūhia e ngā rangahau haumanu-mua ōna pānga aukati nui ki ngā pūtau pukupuku, pērā i ērā i roto i te mate pukupuku repeure me te melanoma, ka whakatūria hei taputapu whai hua mō te rangahau immunotherapy mate pukupuku.
Ka taea e te Tertomotide te whiti i te arai toto-roro, ka taunekeneke ki ngā chaperones pūtau-roto HSP70 me HSP90; ka āraihia e tēnei taunekeneke te whakatakotoranga beta-amyloid me te hyperphosphorylation pūmua tau, ā, ka āraia ngā ara tohu e pā ana ki te koroheketanga o te roro. E whakaatu ana ngā whakamātautau haumanu Wāhanga II i te kaha ki te whakapai ake i te mahi hinengaro i roto i ngā tūroro e pangia ana e te mate a Alzheimer ngawari ki te kino—ina koa mō te tiaki i te mahi reo—ā, ​​kei te haere tonu ngā whakamātautau Wāhanga III.
Kei roto hoki i te Tertomotide te kaha ārai-mumura, e whakaatu ana i ngā pānga tiaki i roto i ngā tauira mate pēnei i te mate rumatiki me te ngaronga o te rongo, ā, kei te tirotirohia i roto i ngā whakamātautau haumanu mō ngā āhuatanga tae atu ki te benign prostatic hyperplasia.